A new study published in BMJ Open this week has suggested an increased risk of death among users of proton pump inhibitors (PPIs), based on records from more than six million patients that compared the use of PPIs, H2 blockers or neither treatment.
The researchers found those taking PPIs had a 25% increased likelihood of death in a six year period compared to those taking the H2 blockers, and that the longer someone took PPIs, the more that risk increased.
Authors were quick to point out that the relationship could only be described as associative, not causative, but still urged caution in the use of PPIs.
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