Pharmacy Daily | Hay fever Rx for IBS

BELGIUM researchers have found hay fever medication could help alleviate symptoms of irritable bowel syndrome (IBS). Researches from KU Leuven were able to identify the link between IBS sufferer’s hypersensitivity and the larger quantities of the substance histamine the patients carry in their bodies. KU Leuven gastroenterology professor Guy Boeckxstaens and his team have shown histamine has an impact on the pain receptor TRPV1. In IBS patients, histamine released in the gut makes TRPV1 hypersensitive. A pilot study found patients who were treated with the antihistamine ebastine for 12 weeks had significantly less abdominal pain than the patients from the control group. A follow up study will evaluate the drug on 200 IBS patients.

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