WOMEN taking hormone replacement therapy (HRT) to manage symptoms of menopause may increase their risk of blood clots, according to a new study released by University of Nottingham researchers in the UK.
The study looked at the prescription records of 80,000 women aged 40-79 who had developed blood clots and compared them with records of 390,000 women who had not.
The risk of blood clots was 15% higher for the treatments containing oestrogen manufactured from horse urine than for the synthetic oestradiol; in real terms, an additional nine cases per 10,000 women per year.
Those using gels, patches or creams (transdermal delivery forms) appeared to have no increased risk of blood-clotting.
More research is needed to confirm a causative association, scientists wrote - see bbc.com.
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