FLINDERS University researchers have analysed how an antidiabetic treatment could help control the growth of tumours, potentially paving the way for the design of better cancer treatments.
The new study investigated what happens when metformin, a type 2 diabetes medication, is used to treat colorectal cancer cells, in the process, demonstrating that it could be exploited to develop new cancer therapies.
"Our work has pinpointed that metformin uses small pieces of RNA (called microRNAs) to act as a 'circuit breaker' and turn off certain genes that are involved in cell growth and division, so it is possible that our findings could eventually be used to develop a new targeted cancer therapy," said lead author Dr Ayla Orang.
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