Aliskiren review

January 11, 2012

THE European Medicines Agency has initiated a review of the aliskiren-containing medicines (which are approved for the treatment of essential hypertension) following the termination of the ALTITUDE study. The trial, which included patients with type 2 diabetes and renal impairment and/or cardiovascular disease who were given aliskiren in addition to either an angiotensin converting enzyme inhibitor or an angiotensin receptor blocker, was terminated in December last year. The early termination of the trial was recommended because its results showed that there was no benefit with aliskiren and that there were more cases of stroke, renal complications, hyperkalemia and hypotension in patients who received aliskiren compared with patients who received a placebo. Whilst the EMA is reviewing the drug’s risk/benefit profile it is advising doctors not to prescribe aliskiren-containing medicines to diabetic patients in combination with ACE inhibitors or ARBs.

The above article was sent to subscribers in Pharmacy Daily's issue from 11 Jan 12
To see the full newsletter, see the embedded issue below or CLICK HERE to download Pharmacy Daily from 11 Jan 12

Other recent headlines

Prescribing endorsement consultation opens
Tuesday | Apr 21 2026
THE Pharmacy Board of Australia has opened public consultation on the draft registration standards and guidelines for a proposed Endorsement for scheduled medicines for pharmacists.

Call for embedded rural pharmacist pilot
Tuesday | Apr 21 2026
AS the Federal Government enters final negotiations for the First Pharmacy Programs Agreement (1PPA), the Remote and Isolated Pharmacist Association Australia (RIPAA) is calling for a dedicated funding pilot to support resident clinical pharmacists in Australia’s most isolated communities.

MTick: Behind the menopause ‘one-stop shop’
Tuesday | Apr 21 2026
UK-BASED organisation GenM founder Heather Jackson (pictured) is on a mission to support pharmacies helping women through menopause with its MTick certification and accreditation.

SEARCH PHARMACY DAILY

Featured video
MORE VIDEOS

Recent issues

PD for Tue 21 Apr 2026
PD for Mon 20 Apr 2026
PD for Fri 17 Apr 2026
PD for Thu 16 Apr 2026
PD for Wed 15 Apr 2026
SEE MORE ISSUES

INDUSTRY JOB VACANCIES

Pharmacist in Charge – SA
Pharmacist Manager – WA
Compounding Pharmacist – Melbourne
Pharmacist in Charge – QLD North
Pharmacist – Sydney North
SEE MORE JOBS

Pharmacy Daily is Australia's favourite online publication dedicated to the pharmacy industry. The publication launched in March 2007 and is distributed every day by email to pharmacists across the country.

PHARMACY DAILY NEWS
Headlines

Jobs

New Products

Events Calendar

FEEDS
News Items RSS feed

PD Issues RSS feed

All content RSS feed

Content & Media
Pharmacy Daily TV

OUR SITES
Sitemap

Travel Daily

Travel Bulletin

Cruise Weekly

Business Events News

Pharmacy Daily

ADVERTISE WITH US
Advertise in Pharmacy Daily

ADMIN
Log in

SUBSCRIBE
Sign up for FREE

Subscription Information

Legal
Privacy

Terms Of Use

Subscription Terms

"Water, air, and cleanness are the chief articles in my pharmacy." - Napoleon Bonaparte

Copyright © 2025 Pharmacy Daily

Subscribe to Pharmacy Daily now!

FREE Pharmacy Daily subscription - never miss another story!

URL
This field is for validation purposes and should be left unchanged.
Name*
First Last
Email*

Profession
Company
Address
City State / Province / Region ZIP / Postal Code Country

By submitting this form I hereby certify that I understand that Pharmacy Daily is a publication for health professionals.

to top

Pharmacy DailyPharmacy Daily | Aliskiren review

Aliskiren review

Other recent headlines

Prescribing endorsement consultation opens

Call for embedded rural pharmacist pilot

MTick: Behind the menopause ‘one-stop shop’

SEARCH PHARMACY DAILY

Featured video

Recent issues

INDUSTRY JOB VACANCIES