THE Annals of Internal Medicine has reaffirmed its commitment to the use of the "safe and inexpensive oral agent" metformin as first line therapy for adults with diabetes type 2 in its updated therapeutic guidelines.
American College of Physicians president Nitin Damle said "metformin, unless contraindicated, is an effective treatment strategy because it has better effectiveness, is associated with fewer adverse effects, and is cheaper than most other oral medications."
The guidelines recommend adding a sulphonylurea, thiazolidinedione, SGLT-2 inhibitor or DPP-4 inhibitor to metformin if a second oral therapy is required - CLICK HERE.
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