AUSTRALIAN researchers are zeroing in on the ultimate quest to regenerate insulin in pancreatic stem cells and replace the need for regular insulin injections for patients.
Baker Heart and Diabetes Institute researchers have demonstrated in the Nature scientific journal that newly made insulin cells can respond to glucose and produce insulin following stimulation with two US Food and Drug Administration-approved drugs in as little as 48 hours.
Further, they confirmed this pathway of awakening the insulin-producing cells is viable in age groups from seven to 61 years, providing much-needed insights into the mechanisms underlying the regeneration of beta cells.
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